[Durgical](https://durgical.com/en/) › [DurgiPedia](https://durgical.com/en/durgipedia/) › [Anatomy](https://durgical.com/en/anatomy/) › [Abdomen](https://durgical.com/en/anatomy/region/abdomen/) › Liver segment V [Digestive system](https://durgical.com/en/anatomy/system/digestive-system/) · [Abdomen](https://durgical.com/en/anatomy/region/abdomen/) # Liver segment V Liver segment V is the lower front part of the right liver, directly under the gallbladder, so gallbladder disease reaches it first. Official name: Anterior medial segment of liver [See in 3D →](https://durgical.app/?from=durgipedia&lang=en#region=abdomen&select=liver_segment_5&side=r) Opens in the Durgical app, no sign-up needed. ## What it is Liver segment V: the lower front part of the right lobe, under the gallbladder. ## What it does Because each segment has its own supply, surgeons can remove one or more segments and leave the rest working. ## Key points - Lies directly under the gallbladder, so gallbladder disease reaches it first: inflammation, perforation into the [liver](https://durgical.com/en/anatomy/liver/) bed and direct invasion by gallbladder cancer - Bounded by the middle hepatic vein on its left (Cantlie line) and the right hepatic vein on its right; the portal plane separates it from liver segment VIII above - With segment VIII it forms the right anterior section; its own portal pedicle guides an anatomical resection, often found by intraoperative ultrasound ## Key facts **Where** Right anterior section, inferior part; gallbladder bed, just right of Cantlie line **Blood supply** Right anterior portal pedicle (right [portal vein](https://durgical.com/en/anatomy/hepatic-portal-vein/), right hepatic artery); drains into middle and right [hepatic veins](https://durgical.com/en/anatomy/hepatic-veins/) **Nerve** Hepatic plexus (celiac sympathetic and vagal fibres) along its portal pedicle, shared with the whole liver **Function** Independent surgical unit; bile to right anterior sectoral duct; with IVb it is resected in radical gallbladder surgery ## Relations **Above** [Liver segment VIII](https://durgical.com/en/anatomy/posterior-medial-segment-of-liver/), above the plane of the portal bifurcation **Medial** [Liver segment IV](https://durgical.com/en/anatomy/left-medial-segment-of-liver/) (IVb), across Cantlie line and the middle hepatic vein **Lateral** [Liver segment VI](https://durgical.com/en/anatomy/anterior-lateral-segment-of-liver/), beyond the plane of the right hepatic vein **Below** [Gallbladder](https://durgical.com/en/anatomy/gallbladder/) in its fossa, hepatic flexure of the colon and the first part of the [duodenum](https://durgical.com/en/anatomy/duodenum/) ## How to find it At the lower edge of the right liver where the gallbladder fundus meets the right costal margin, near the tip of the ninth [costal cartilage](https://durgical.com/en/anatomy/costal-cartilage/) in the midclavicular line; it is the liver bed exposed in every cholecystectomy. ## On imaging On CT or MRI it lies below the portal plane, between the middle and right hepatic veins, beside the gallbladder fossa. Focal fatty sparing next to the gallbladder can look like a nodule on ultrasound. ## Common problems - Fatty liver disease, very common with obesity and diabetes. - Hepatitis (viral, alcohol). - Cirrhosis: scarring that can lead to liver failure and portal hypertension. - Liver cancer and metastases. ## How it is diagnosed Blood tests (liver enzymes), ultrasound, elastography, CT or MRI, biopsy. ## Treatment - Treat the cause (weight loss, antiviral medicines, stopping alcohol); surgery to remove segments; liver transplant for failure. ## Clinical notes - Bleeding from the liver bed during cholecystectomy comes from this segment; in some people a branch of the middle hepatic vein runs just under the gallbladder fossa - Small subvesical ducts (ducts of Luschka) in the gallbladder bed can leak bile after cholecystectomy ## Anatomical variants - A branch of the middle hepatic vein running just under the gallbladder bed in some people, a source of brisk bleeding at cholecystectomy ## Related conditions - [Gallbladder cancer](https://durgical.com/en/conditions/gallbladder-cancer/) ## Test yourself Think of the answer, then tap the question to see it. ## Which liver segment lies directly under the gallbladder? Liver segment V (with IVb), so gallbladder inflammation, perforation and cancer reach it first. ## Which hepatic veins bound liver segment V? The middle hepatic vein on its left (Cantlie line) and the right hepatic vein on its right; the portal plane separates it from segment VIII above. ## What can leak bile from the liver bed after cholecystectomy? Small subvesical ducts (ducts of Luschka) in the gallbladder bed over liver segment V. [Add to my cards (3)](https://durgical.app/estudiar/?add=/en/anatomy/anterior-medial-segment-of-liver/) Educational information, not medical advice. For any symptom, see a health professional. ## Its names **Official Latin (TA2)** segmentum anterius mediale dextrum hepatis TA2 3076 **Official Spanish (DeCS)** Segmento V del hígado DeCS D008099 **English (TA2)** Anterior medial segment of liver **Also called** segment V of liver ## Related - [Gallbladder](https://durgical.com/en/anatomy/gallbladder/) Sources: Terminologia Anatomica (TA2); [DeCS](https://decs.bvsalud.org/es/ths/resource/?id=8272); [Diagnostic Imaging of the Liver](https://www.ncbi.nlm.nih.gov/books/NBK557460/); [Anatomy, Abdomen and Pelvis: Liver](https://www.ncbi.nlm.nih.gov/books/NBK500014/); [23.6 Accessory Organs in Digestion: The Liver, Pancreas, and Gallbladder](https://openstax.org/books/anatomy-and-physiology-2e/pages/23-6-accessory-organs-in-digestion-the-liver-pancreas-and-gallbladder) (OpenStax (Rice University), 2022) · adapted, [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/). ## **Spotted a mistake?** We are always improving for the community. Tell us what is wrong and our team will review it. Report a mistake Representative model, for educational purposes only. --- Source: https://durgical.com/en/anatomy/anterior-medial-segment-of-liver/ License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/anatomy/anterior-medial-segment-of-liver/