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# C2–C3 nucleus

The nucleus pulposus is the soft, gel-like centre of the [C2-C3](https://durgical.com/en/anatomy/c2-c3/) disc in the neck; it works like a water cushion that spreads the load.

Official name: C2-C3

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## What it is

The soft, gel-like centre (nucleus pulposus) of the C2–C3 disc.

## What it does

Works like a water cushion: it turns pressure from above into outward push on the fibre ring, spreading the load. It is under the most pressure when you bend forward and lift.

## Key points

- In the neck, a foraminal herniation and a posterolateral one hit the same root (here C3), because each cervical root runs almost horizontally out of its foramen
- Cervical nuclei are small and, by middle age, largely fibrous, so a soft herniation at C2–C3 is rare

## Key facts

**Where**
Centre of the C2–C3 disc, slightly toward the back, inside the annulus fibrosus

**Function**
Notochord-derived gel (about 70–90% water, proteoglycans); turns axial load into annulus tension; herniates posterolaterally toward the C3 root

## Relations

**Behind**
Back of the annulus fibrosus and the [posterior longitudinal ligament](https://durgical.com/en/anatomy/posterior-longitudinal-ligament/), broad here and continuing upward as the tectorial membrane, then the [spinal cord](https://durgical.com/en/anatomy/spinal-cord/)

**Lateral**
Uncovertebral joints of C3, with the C3 root behind them and the [vertebral artery](https://durgical.com/en/anatomy/vertebral-artery/) in the transverse foramina further out

## How to find it

From the front, at about the height of the angle of the [mandible](https://durgical.com/en/anatomy/mandible/), just above the [hyoid bone](https://durgical.com/en/anatomy/hyoid-bone/) (about C3). The nucleus sits in the middle of the disc, deep behind the [pharynx](https://durgical.com/en/anatomy/pharynx/).

## On imaging

In a congenital C2–C3 block, the lateral X-ray shows a narrow «wasp waist» where the disc should be, and MRI shows no nucleus.

## Common problems

- Squeezes out through a tear in the ring (herniation), usually backward and to one side, toward a nerve root.
- Loses water with age, so the disc gets thinner and stiffer.

## How it is diagnosed

On MRI a healthy nucleus is bright on T2 images; a worn one turns dark ('black disc').

## Treatment

- In a microdiscectomy only the loose piece that has pushed out is removed; most of the disc stays.

## Clinical notes

- A C3 root lesion gives upper neck and back-of-head pain with no dependable weakness or reflex change, so it is hard to tell from facet or muscle pain
- Anterior surgery at C2–C3 lies high under the jaw, near the hypoglossal and superior laryngeal nerves, which makes it harder than at lower levels

## Anatomical variants

- Congenital fusion of C2 and C3, alone or as part of Klippel–Feil syndrome, is the most frequent cervical fusion; the disc and its nucleus are then absent or reduced to a thin remnant

## Development

Like every nucleus pulposus it comes from the notochord. There is no disc above it: the dens is the body of the [atlas](https://durgical.com/en/anatomy/atlas/) fused to the [axis](https://durgical.com/en/anatomy/axis/), and the cartilage line at its base (subdental synchondrosis), a remnant of a disc, can be mistaken for a fracture in young children.

## Test yourself

Think of the answer, then tap the question to see it.

## Which root does a posterolateral herniation of the C2–C3 nucleus reach, and why does a foraminal one reach the same root?

The C3 root; each cervical root runs almost horizontally out of its foramen, so both herniation sites hit the same root.

## Why is a soft herniation of the C2–C3 nucleus rare?

Cervical nuclei are small and, by middle age, largely fibrous.

## How does a congenital C2–C3 block look on imaging?

The lateral X-ray shows a narrow «wasp waist» where the disc should be, and MRI shows no nucleus.

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Educational information, not medical advice. For any symptom, see a health professional.

## Its names

**Official Latin (TA2)**
nucleus pulposus C2-C3 TA2 1686

**Official Spanish (DeCS)**
Núcleo pulposo C2-C3 DeCS D000070614

**English (TA2)**
C2-C3

## Related

- [C2–C3 disc](https://durgical.com/en/anatomy/c2-c3/)
- [Axis (C2)](https://durgical.com/en/anatomy/axis/)
- [C3 vertebra](https://durgical.com/en/anatomy/cervical-vertebrae/)

Sources: Terminologia Anatomica (TA2); [DeCS](https://decs.bvsalud.org/es/ths/resource/?id=56248&filter=ths_termall&q=N%C3%BAcleo%20Pulposo); [Anatomy, Back, Nucleus Pulposus](https://www.ncbi.nlm.nih.gov/books/NBK535373/); [Anatomy, Back, Intervertebral Discs](https://www.ncbi.nlm.nih.gov/books/NBK470583/); Anatomy of the Human Body (20th ed.): Articulations of the Vertebral Column (Lea & Febiger (Gray's Anatomy, 1918), 1918) · adapted, Public domain.

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Representative model, for educational purposes only.

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Source: https://durgical.com/en/anatomy/c2-c3-spine-and-pelvis/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/anatomy/c2-c3-spine-and-pelvis/
