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# Vermis

The vermis is the narrow middle strip of the [cerebellum](https://durgical.com/en/anatomy/anterior-quadrangular-lobule/); it controls trunk balance and walking and is the first part damaged by alcohol.

Official name: Central lobule

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## What it is

The narrow middle strip of the cerebellum.

## What it does

Controls trunk balance and walking; alcohol damages it first.

## Key points

- Midline lesions cause truncal ataxia: a broad-based, staggering gait and swaying when sitting or standing, while finger-to-nose may be normal
- Chronic alcohol use degenerates the upper front vermis first, so walking and heel-to-shin fail while the arms are spared
- In children, medulloblastoma usually arises in the vermis, fills the fourth ventricle and causes obstructive hydrocephalus with morning vomiting and unsteadiness
- The fastigial nucleus lies under it; with the nodulus (flocculonodular lobe) it controls balance and eye movements through the vestibular nuclei

## Key facts

**Where**
Midline of the cerebellum

**Blood supply**
SCA, PICA

**Function**
Trunk balance and gait (damaged first by alcohol)

## Relations

**Lateral**
Cerebellar hemispheres, through the paravermal zone

**In front**
Roof of the [fourth ventricle](https://durgical.com/en/anatomy/fourth-ventricle/): superior medullary velum above; nodulus and inferior medullary velum below

**Above**
[Tentorium cerebelli](https://durgical.com/en/anatomy/tentorium-cerebelli/) at its junction with the [falx cerebri](https://durgical.com/en/anatomy/falx-cerebri/), which holds the [straight sinus](https://durgical.com/en/anatomy/straight-sinus/); the great cerebral vein in front

**Below**
Vallecula between the [cerebellar tonsils](https://durgical.com/en/anatomy/tonsil-of-cerebellum/), opening onto the cisterna magna

**Behind**
Posterior cerebellar notch with the falx cerebelli and the internal occipital crest

## How to find it

It cannot be felt. On midline sagittal MRI it is the branching central strip of the cerebellum behind the fourth ventricle; front to back its lobules are lingula, central lobule, culmen, declive, folium, tuber, pyramid, uvula and nodulus, the primary fissure lying between culmen and declive. Surgeons reach it through a midline suboccipital opening, between the hemispheres.

## Examination

- Tandem gait (heel to toe along a straight line): a vermis lesion makes it fail early, with a wide-based, lurching walk, even when finger-to-nose and heel-to-shin are nearly normal
- Balance sitting and standing with the eyes open: swaying of the trunk or the need to stand with the feet far apart points to a midline cerebellar problem
- Romberg test: with a vermis lesion the person is already unsteady with the eyes open and closing them adds little; clear worsening only when the eyes close points instead to loss of position sense

## On imaging

Sagittal MRI shows its full outline. Dandy–Walker malformation: a small or absent vermis with a cystic fourth ventricle in an enlarged posterior fossa. Joubert syndrome: vermis hypoplasia with a 'molar tooth' [midbrain](https://durgical.com/en/anatomy/midbrain/) on axial images.

## Clinical notes

- Splitting the vermis to reach the fourth ventricle in children can be followed, a day or more later, by cerebellar mutism (posterior fossa syndrome): loss of speech with irritability that usually improves over weeks to months
- Dandy–Walker malformation: a small, upwardly rotated vermis with a cystic, enlarged fourth ventricle and a large posterior fossa; often seen on prenatal ultrasound, and many children develop hydrocephalus
- A stroke or bleed in the vermis can present as sudden vertigo with inability to stand or walk while the limbs move well; it mimics an inner ear disorder and is easily missed

## Development

The two cerebellar plates, from the rhombic lips of the hindbrain, fuse in the midline to form the vermis; failure of this growth underlies vermian hypoplasia.

## Memory aid

Vermis = midline = trunk; hemispheres = limbs on the same side.

## Related conditions

- [Wernicke encephalopathy (thiamine deficiency)](https://durgical.com/en/conditions/wernicke-encephalopathy/)
- [Ataxia-telangiectasia](https://durgical.com/en/conditions/ataxia-telangiectasia/)
- [Childhood brain tumours (medulloblastoma, pilocytic astrocytoma, craniopharyngioma)](https://durgical.com/en/conditions/childhood-brain-tumours/)
- [Spinocerebellar ataxias (autosomal dominant ataxias)](https://durgical.com/en/conditions/spinocerebellar-ataxias/)

## Test yourself

Think of the answer, then tap the question to see it.

## What does a lesion of the cerebellar vermis cause?

Truncal ataxia: a broad-based, staggering gait and swaying when sitting or standing, while finger-to-nose may be normal.

## Which part of the vermis does chronic alcohol use damage first, and what fails?

The upper front vermis: walking and heel-to-shin fail while the arms are spared.

## How does a medulloblastoma of the vermis present in a child?

It fills the fourth ventricle and causes obstructive hydrocephalus, with morning vomiting and unsteadiness.

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Educational information, not medical advice. For any symptom, see a health professional.

## Its names

**Official Latin (TA2)**
lobulus centralis vermis TA2 5821

**Official Spanish (DeCS)**
Vermis Cerebeloso DeCS D065814

**English (TA2)**
Central lobule

**Also called**
lobus centralis vermis

## Related

- [Cerebellar arteries](https://durgical.com/en/anatomy/superior-cerebellar-artery/)

Sources: Terminologia Anatomica (TA2); [DeCS](https://decs.bvsalud.org/es/ths/resource/?id=55496); [Neuroanatomy, Cerebellum](https://www.ncbi.nlm.nih.gov/books/NBK538167/); [Neuroanatomy, Nucleus Fastigial](https://www.ncbi.nlm.nih.gov/books/NBK547738/); [16.5 The Coordination and Gait Exams](https://openstax.org/books/anatomy-and-physiology-2e/pages/16-5-the-coordination-and-gait-exams) (OpenStax (Rice University), 2022) · adapted, [CC BY 4.0](https://creativecommons.org/licenses/by/4.0/); Tratado de anatomía humana (9.ª ed.), tomo II, Libro V, sección 2 (Encéfalo), capítulos I-V: bulbo, protuberancia, cerebelo, cuarto ventrículo, mesencéfalo.

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Representative model, for educational purposes only.

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Source: https://durgical.com/en/anatomy/central-lobule/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/anatomy/central-lobule/
