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# Vitreous

The vitreous is the clear gel filling the back of the eye; it keeps the eye's shape, and clumps in it cast the shadows called floaters.

Official name: Vitreous body

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## What it is

The clear gel filling the back of the eye.

## What it does

Keeps the eye's shape; clumps in it cast the shadows called floaters.

## Key points

- Mostly water held in a framework of collagen and hyaluronic acid; attached most firmly at the vitreous base over the ora serrata, and less so at the optic disc, the macula and along vessels
- Posterior vitreous detachment is common with age; if it tears the retina, a retinal detachment can follow, so new flashes and floaters are checked with a dilated retinal exam
- Vitreous haemorrhage: proliferative diabetic retinopathy, a retinal tear or trauma; Terson syndrome is bleeding into the eye with a subarachnoid haemorrhage
- It does not regenerate: after vitrectomy the space fills with aqueous, gas or silicone oil

## Key facts

**Where**
Fills the space between the lens and the retina (~80% of the eye)

**Blood supply**
Avascular

**Function**
Keeps the eye's shape; transparent path for light

## Relations

**In front**
Back of the [lens](https://durgical.com/en/anatomy/lens/), which sits in its hyaloid fossa, and the [zonular fibres](https://durgical.com/en/anatomy/ciliary-zonule/)

**Behind**
[Optic disc](https://durgical.com/en/anatomy/optic-disc/) and [macula](https://durgical.com/en/anatomy/macula/), where the posterior hyaloid face adheres

**Superficial**
[Retina](https://durgical.com/en/anatomy/retina/), against the internal limiting membrane, and the pars plana of the [ciliary body](https://durgical.com/en/anatomy/ciliary-body/) at its base

**Contents**
Cloquet canal, the path of the former hyaloid artery from disc to lens, and scattered cells (hyalocytes)

## How to find it

Seen at the slit lamp just behind the lens (anterior vitreous) and with the ophthalmoscope as a clear space; floaters and pigment drift in it as the eye moves.

## Examination

- Slit lamp of the anterior vitreous: pigment cells (tobacco dust, Shafer sign) after a posterior vitreous detachment strongly suggest a retinal tear
- Fundoscopy: a floating ring in front of the disc (Weiss ring) marks a posterior vitreous detachment

## On imaging

B-scan ultrasound shows the detached posterior hyaloid, and any retinal detachment, when blood blocks the view; OCT shows vitreomacular traction.

## Common problems

- Floaters: specks and cobwebs from clumping gel, common with age.
- Posterior vitreous detachment: the gel peels off the retina; a sudden burst of floaters needs a retina check.
- Vitreous haemorrhage, often from diabetic vessels.

## How it is diagnosed

Dilated eye exam; ultrasound when blood blocks the view.

## Treatment

- Usually no treatment for floaters.
- Vitrectomy (removing the gel) for persistent bleeding or retinal problems.

## Clinical notes

- Injections into the vitreous (anti-VEGF drugs, steroids, antibiotics) and vitrectomy instruments enter through the pars plana
- Endophthalmitis: infection of the vitreous after surgery or injury; a sample is taken from it for culture
- Asteroid hyalosis: many small white calcium-lipid particles, usually harmless
- Persistent fetal vasculature (persistent hyperplastic primary vitreous) causes leukocoria and a small eye in infants

## Anatomical variants

- Remnants of the fetal hyaloid artery are common and harmless: a small dot on the back of the lens capsule (Mittendorf dot) or a tuft of glial tissue on the disc (Bergmeister papilla)

## Development

The primary vitreous, which holds the hyaloid vessels, is replaced by the avascular secondary vitreous; the tertiary vitreous forms the zonular fibres.

## Related conditions

- [Retinal detachment](https://durgical.com/en/conditions/retinal-detachment/)
- [Ocular toxoplasmosis (retinochoroiditis)](https://durgical.com/en/conditions/ocular-toxoplasmosis/)
- [Endophthalmitis](https://durgical.com/en/conditions/endophthalmitis/)

## Test yourself

Think of the answer, then tap the question to see it.

## Why are new flashes and floaters checked with a dilated retinal exam?

They may mean a posterior vitreous detachment that has torn the retina, which can lead to retinal detachment.

## Where is the vitreous body attached most firmly?

At the vitreous base over the ora serrata; less so at the optic disc, the macula and along vessels.

## What does «tobacco dust» (Shafer sign) in the anterior vitreous suggest?

A retinal tear, after a posterior vitreous detachment.

## What is Terson syndrome?

Bleeding into the eye (vitreous haemorrhage) with a subarachnoid haemorrhage.

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Educational information, not medical advice. For any symptom, see a health professional.

## Its names

**Official Latin (TA2)**
corpus vitreum TA2 6809

**Official Spanish (DeCS)**
Cuerpo Vítreo DeCS D014822

**English (TA2)**
Vitreous body

**Also called**
vitreous humour

## Related

- [Lens](https://durgical.com/en/anatomy/lens/)
- [Retina](https://durgical.com/en/anatomy/retina/)

Sources: Terminologia Anatomica (TA2); [DeCS](https://decs.bvsalud.org/es/ths/resource/?id=15224&filter=ths_termall&q=Vitreous%20Body); [Posterior Vitreous Detachment](https://www.ncbi.nlm.nih.gov/books/NBK563273/); [Anatomy, Head and Neck, Eye](https://www.ncbi.nlm.nih.gov/books/NBK482428/).

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Representative model, for educational purposes only.

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Source: https://durgical.com/en/anatomy/vitreous-body/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/anatomy/vitreous-body/
