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# Vocal folds

The vocal folds (vocal cords) are two bands of muscle and ligament across the larynx; they vibrate to make the voice and close to protect the airway.

Official name: Vocal fold

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## What it is

Two bands of muscle and ligament stretched across the larynx from front to back.

## What it does

Vibrate to make the voice and close to protect the airway.

## Key points

- Layers: epithelium, a loose superficial lamina propria (Reinke space), the vocal ligament and the vocalis muscle; the loose cover glides over the body to make the mucosal wave
- Glottic cancer causes hoarseness early and the true folds have few lymphatics, so early tumours rarely reach the nodes and have a good prognosis
- Nodules are bilateral, at the junction of the front and middle thirds, from voice overuse; polyps are usually one-sided
- The glottis (folds plus the gap between them, the rima glottidis) is classically taught as the narrowest part of the adult larynx

## Key facts

**Attaches**
Inner angle of the thyroid cartilage to the vocal processes of the arytenoids

**Function**
Produce voice; close the airway (cough, effort)

**Tight in**
[Cricothyroid](https://durgical.com/en/anatomy/oblique-part-of-cricothyroid-muscle/) contraction (high pitch)

## Relations

**Above**
Laryngeal ventricle, then the vestibular (false) folds

**Below**
Conus elasticus and the subglottic space, down to the [cricoid cartilage](https://durgical.com/en/anatomy/cricoid-cartilage/)

**Lateral**
[Thyroarytenoid](https://durgical.com/en/anatomy/musculus-thyreoarytenoideus/) muscle, paraglottic space and the [thyroid cartilage](https://durgical.com/en/anatomy/thyroid-cartilage/) lamina

**In front**
[Anterior commissure](https://durgical.com/en/anatomy/anterior-commissure/), where the two folds meet behind the thyroid cartilage

**Behind**
Vocal processes of the [arytenoid cartilages](https://durgical.com/en/anatomy/arytenoid-cartilage/) and the interarytenoid region (posterior commissure)

## How to find it

Seen with a laryngeal mirror, a flexible nasal endoscope or a rigid endoscope as two pearly white bands in a V with the point in front; they open on breathing in and meet on a sustained vowel. Stroboscopy shows the mucosal wave.

## On imaging

Laryngoscopy with stroboscopy is the main examination. CT and MRI stage cancer by looking at the paraglottic space, the anterior commissure and the laryngeal cartilages.

## Common problems

- Laryngitis and overuse: hoarseness.
- Nodules and polyps from voice strain (singers, teachers).
- Paralysis from [recurrent laryngeal nerve](https://durgical.com/en/anatomy/recurrent-laryngeal-nerve/) injury.
- Hoarseness for more than 3 weeks, especially in smokers, needs a check for cancer.

## How it is diagnosed

Laryngoscopy (a camera to look at the vocal folds).

## Treatment

- Voice rest and voice therapy.
- Microsurgery for polyps; treatment of cancer by surgery or radiotherapy.

## Clinical notes

- Reinke oedema: smoking-related swelling of the superficial lamina propria, giving a low, husky voice
- Recurrent respiratory papillomatosis: HPV-related warty growths (mainly types 6 and 11) in children and adults, which tend to come back
- Vocal fold dysfunction (the folds close on breathing in) can mimic asthma

## Development

The laryngeal lumen closes and then reopens in the embryo; incomplete reopening leaves a laryngeal web, usually across the front of the glottis.

## Related conditions

- [Farber disease (Farber lipogranulomatosis)](https://durgical.com/en/conditions/farber-disease/)
- [Laryngeal cancer](https://durgical.com/en/conditions/laryngeal-cancer/)
- [Anaphylaxis](https://durgical.com/en/conditions/anaphylaxis/)
- [Botulism](https://durgical.com/en/conditions/botulism/)
- [Vocal fold nodules, polyps and laryngitis](https://durgical.com/en/conditions/vocal-fold-nodules-polyps-and-laryngitis/)
- [Vocal fold paralysis (recurrent laryngeal nerve injury)](https://durgical.com/en/conditions/vocal-fold-paralysis/)
- [Croup (laryngotracheobronchitis)](https://durgical.com/en/conditions/croup/)
- [Cri-du-chat syndrome (5p deletion)](https://durgical.com/en/conditions/cri-du-chat-syndrome/)

## Test yourself

Think of the answer, then tap the question to see it.

## What are the layers of the vocal fold, and which one produces the mucosal wave?

Epithelium, superficial lamina propria (Reinke space), vocal ligament and vocalis muscle; the loose superficial cover glides over the body to make the mucosal wave.

## Why does early glottic cancer have a good prognosis?

It causes hoarseness early, and the true vocal folds have few lymphatics, so early tumours rarely reach the neck nodes.

## Where do vocal fold nodules form and how do they differ from polyps?

Bilaterally at the junction of the front and middle thirds, from voice overuse; polyps are usually one-sided.

## Which muscle tenses the vocal folds to raise pitch?

The cricothyroid, which tilts the thyroid cartilage forward and lengthens the folds.

## What is Reinke oedema?

Smoking-related swelling of the superficial lamina propria (Reinke space) of the vocal folds, giving a low, husky voice.

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Educational information, not medical advice. For any symptom, see a health professional.

## Its names

**Official Latin (TA2)**
plica vocalis TA2 3198

**Official Spanish (DeCS)**
Pliegues Vocales DeCS D014827

**English (TA2)**
Vocal fold

**Also called**
vocal cords · labium vocale

## Related

- [Arytenoid cartilages](https://durgical.com/en/anatomy/arytenoid-cartilage/)

Sources: Terminologia Anatomica (TA2); [DeCS](https://decs.bvsalud.org/es/ths/resource/?id=15228); [Anatomy, Head and Neck, Larynx Vocal Cords](https://www.ncbi.nlm.nih.gov/books/NBK535342/).

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Source: https://durgical.com/en/anatomy/vocal-fold/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/anatomy/vocal-fold/
