[Durgical](https://durgical.com/en/) › [DurgiPedia](https://durgical.com/en/durgipedia/) › [General pathology](https://durgical.com/en/general-pathology/) › [Gastrointestinal tract](https://durgical.com/en/general-pathology/areas/gi/) › Intestinal helminths

# Intestinal helminths

- Lesion

Worms living in the gut can block it, bleed it, cause anaemia or itching, and some invade the wall and the whole body.

Updated Nov 12, 2026

## Key points

- Ascaris: eggs from soil; larvae migrate through liver and lungs (pneumonitis), adults in the small bowel; masses of worms obstruct the bowel or bile ducts.
- Strongyloides: larvae penetrate skin; autoinfection lets it persist for life; overwhelming hyperinfection with steroids or HTLV-1.
- Hookworms (Necator, Ancylostoma): skin entry, attach to the duodenum and suck blood: iron deficiency anaemia.
- Trichuris (whipworm) and Enterobius (pinworm) do not invade: heavy whipworm loads cause bloody diarrhoea and rectal prolapse in children; pinworms lay eggs on the perianal skin at night, causing itching (tape test).
- Schistosoma: adults in mesenteric veins; eggs trapped in the wall cause granulomas, bleeding and fibrosis; also portal fibrosis.
- Tapeworms (Diphyllobothrium, Taenia, Hymenolepis): stay in the lumen; fish tapeworm can cause B12 deficiency.

## What it is

Parasitic infections affect more than half of the world's population on a chronic or recurrent basis. Soil-transmitted helminths (Ascaris, Strongyloides, hookworms and whipworm) are common where sanitation is poor, including rural Colombia. Worms that invade tissue provoke eosinophilia; those that stay in the lumen (pinworms, tapeworms) usually do not. Each worm leaves a characteristic lesion.

## Intestinal worms: route, lesion and consequence

| Worm | Route | Tissue reaction | Main consequence |
| --- | --- | --- | --- |
| [Ascaris lumbricoides](https://durgical.com/en/conditions/soil-transmitted-helminthiasis/) | Eggs swallowed | Eosinophil-rich inflammation; lung passage | Bowel or biliary obstruction, liver abscess |
| [Strongyloides stercoralis](https://durgical.com/en/conditions/strongyloidiasis/) | Larvae through skin; autoinfection | Eosinophilia, larvae in the mucosa | Lifelong infection, hyperinfection when immunosuppressed |
| [Hookworms](https://durgical.com/en/conditions/iron-deficiency-anaemia/) | Larvae through skin | Erosions, focal haemorrhage | Iron deficiency anaemia |
| [Trichuris trichiura](https://durgical.com/en/conditions/soil-transmitted-helminthiasis/) | Eggs swallowed | Little invasion | Bloody diarrhoea, rectal prolapse |
| Enterobius vermicularis | Eggs, fingers to mouth | None (luminal) | Perianal itching |
| Schistosoma (intestinal) | Cercariae through skin | Granulomas around trapped eggs | Bleeding, obstruction, portal fibrosis |
| [Tapeworms](https://durgical.com/en/conditions/intestinal-tapeworm-infections/) | Raw or undercooked fish, beef, pork | None (luminal); no eosinophilia | Usually mild; fish tapeworm takes B12 |

## Clinical notes

- Before steroids or other immunosuppression, people from endemic regions should be screened or treated for Strongyloides.
- Diagnosis is usually by eggs or larvae in stool; pinworm by perianal tape; tapeworm by proglottids.

## Memory aid

Invaders bring eosinophils; lodgers in the lumen do not.

## Test yourself

Think of the answer, then tap the question to see it.

## Which intestinal worm can complete its life cycle inside the human host, causing lifelong infection?

Strongyloides stercoralis, through autoinfection.

## Which worm causes iron deficiency anaemia by attaching to the duodenal mucosa and sucking blood?

Hookworms (Necator americanus and Ancylostoma duodenale).

## Which tapeworm can cause vitamin B12 deficiency?

Diphyllobothrium latum, the fish tapeworm, which competes for dietary B12.

## Why do tapeworm infections rarely cause eosinophilia?

The worm stays in the lumen and does not invade tissue.

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## Elsewhere in DurgiPedia

- [Eosinophil](https://durgical.com/en/immunology/eosinophil/)

## Connections

## Related 4

- [Infectious enterocolitis](https://durgical.com/en/general-pathology/infectious-enterocolitis/)
- [Intestinal protozoa: amoebic flask ulcers, Giardia and Cryptosporidium](https://durgical.com/en/general-pathology/intestinal-protozoa-amoebic-flask-ulcers-giardia-and-cryptosporidium/)
- [Acute appendicitis](https://durgical.com/en/general-pathology/acute-appendicitis/)
- [Liver infections: bacterial, fungal and parasitic](https://durgical.com/en/general-pathology/liver-infections-bacterial-fungal-and-parasitic/)

## Related conditions 6

- [Soil-transmitted helminthiasis (ascariasis, hookworm, trichuriasis)](https://durgical.com/en/conditions/soil-transmitted-helminthiasis/)
- [Strongyloidiasis](https://durgical.com/en/conditions/strongyloidiasis/)
- [Intestinal tapeworm infections (taeniasis, hymenolepiasis, diphyllobothriasis)](https://durgical.com/en/conditions/intestinal-tapeworm-infections/)
- [Iron deficiency anaemia](https://durgical.com/en/conditions/iron-deficiency-anaemia/)
- [Megaloblastic anaemia (B12 or folate deficiency)](https://durgical.com/en/conditions/megaloblastic-anaemia/)
- [Rectal prolapse](https://durgical.com/en/conditions/rectal-prolapse/)

## Microorganisms 6

- [Ascaris lumbricoides](https://durgical.com/en/microbiology/ascaris-lumbricoides/)
- [Strongyloides stercoralis](https://durgical.com/en/microbiology/strongyloides-stercoralis/)
- [Necator americanus / Ancylostoma duodenale](https://durgical.com/en/microbiology/necator-americanus-ancylostoma-duodenale/)
- [Trichuris trichiura](https://durgical.com/en/microbiology/trichuris-trichiura/)
- [Enterobius vermicularis](https://durgical.com/en/microbiology/enterobius-vermicularis/)
- [Schistosoma mansoni / S. haematobium / S. japonicum](https://durgical.com/en/microbiology/schistosoma-mansoni-s-haematobium-s-japonicum/)

[← All of general pathology](https://durgical.com/en/general-pathology/)

Educational content on the mechanisms of disease; not a diagnostic or treatment guide and no substitute for a health professional's advice. No doses are given.

Sources: [Soil-transmitted helminth infections](https://www.who.int/news-room/fact-sheets/detail/soil-transmitted-helminth-infections) (World Health Organization, 2023); [Tapeworm Infections and Cysticercosis](https://www.ncbi.nlm.nih.gov/books/NBK537154/) (StatPearls (NCBI Bookshelf), 2025).

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Source: https://durgical.com/en/general-pathology/intestinal-helminths/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/general-pathology/intestinal-helminths/
