[Durgical](https://durgical.com/en/) › [DurgiPedia](https://durgical.com/en/durgipedia/) › [Nursing](https://durgical.com/en/nursing/) › [Critical care](https://durgical.com/en/nursing/areas/critical-care/) › Nursing the patient with ARDS: lung-protective ventilation, oxygenation goals, fluids and positioning

# Nursing the patient with ARDS: lung-protective ventilation, oxygenation goals, fluids and positioning

- Safe practice

Low tidal volumes by predicted weight, plateau pressure checks, the ordered oxygen target, careful fluids and prone position when ordered.

Updated Nov 13, 2026

## Key points

- Low tidal volumes calculated from predicted body weight, as the protocol says; predicted weight comes from sex and height, so measure height.
- Plateau pressure below 30 cmH2O (WHO), checked at least every 4 h and after each PEEP or volume change.
- Oxygenation goal in the ARDSNet protocol of the WHO toolkit: PaO2 55–80 mmHg or SpO2 88–95%, unless the team sets another.
- Conservative fluids when there is no hypoperfusion: it shortens time on the ventilator.
- Prone position for PaO2/FiO2 below 150 mmHg, in long sessions (WHO 12–16 h; ESICM 16 h or more).
- Avoid disconnections: in-line suction, and clamp the tube as the protocol says if a disconnection is needed.

## What it is

In ARDS the lungs are stiff and unevenly injured, and the ventilator itself can add injury. Care follows a lung-protective protocol agreed by the team: low tidal volumes calculated from predicted body weight, a limited plateau pressure, PEEP and FiO2 adjusted by protocol, a conservative fluid strategy when there is no hypoperfusion, and prone position in moderate to severe cases. The nurse makes the protocol work at the bedside: accurate height, careful checks, no unnecessary disconnections, strict fluid balance, prevention of complications and early warning of deterioration. The disease itself is described on the ARDS condition page.

## What it requires

- A lung-protective ventilation protocol agreed by the team.
- Arterial blood gases, and often an arterial line for invasive blood pressure.
- Staff trained to turn the patient prone.
- Strict fluid balance and daily weight when the protocol asks for it.

## Components

- Low tidal volume by predicted body weight and a limited plateau pressure.
- PEEP and FiO2 adjusted by a protocol table or as ordered.
- An oxygenation target set by the team.
- Conservative fluid strategy without hypoperfusion.
- Prone position for moderate to severe ARDS.
- Sedation, and neuromuscular blockers only in selected situations, not routinely.

## How it is applied (and why)

- Measure height accurately and confirm sex for predicted body weight — tidal volume targets depend on it, not on actual weight.
- Check the delivered tidal volume against the ordered target at each check — larger volumes injure the lung.
- Measure the plateau pressure with an inspiratory pause at least every 4 h and after changes; report it above 30 cmH2O.
- Change FiO2 and PEEP only as the protocol or order says, watching SpO2, blood pressure and comfort — PEEP can lower blood pressure.
- Use in-line suction and avoid disconnecting; if it is needed, clamp the tube as the protocol says — loss of PEEP collapses lung units.
- Keep a strict fluid balance and report a rising positive balance — a conservative strategy shortens ventilation.
- Prepare for prone position when PaO2/FiO2 stays below 150 mmHg — long prone sessions reduce mortality.
- Assess sedation and comfort; if a neuromuscular blocker is ordered, confirm adequate sedation first — a paralysed patient cannot show distress.
- Prevent complications: head up, oral care, turning, early enteral feeding and mobilisation when stable.
- Watch for pneumothorax: sudden high pressures, falling SpO2, unequal chest movement or hypotension — call at once.

## In nursing practice

- Permissive hypercapnia is accepted: a higher PaCO2 is tolerated to keep volumes and pressures low.
- Neuromuscular blockers are not used routinely; they may be considered for severe asynchrony or refractory hypoxaemia.
- Prolonged high-pressure recruitment manoeuvres are not recommended (ESICM).
- For refractory hypoxaemia despite lung-protective ventilation, the team may consider referral for ECMO in expert centres.

## Common mistakes

- Using the actual body weight instead of the predicted body weight.
- Not measuring the plateau pressure after changes.
- Giving extra fluid when there is no sign of hypoperfusion.
- Delaying prone position, or stopping daily prone sessions only because oxygenation did not improve.

## Test yourself

Think of the answer, then tap the question to see it.

## On what weight is the lung-protective tidal volume based?

On predicted body weight, calculated from sex and height, not on the actual weight.

## What plateau pressure limit does WHO give for lung-protective ventilation?

Below 30 cmH2O, checked with an inspiratory pause at least every 4 hours and after changes.

## Why is a conservative fluid strategy used in ARDS without hypoperfusion?

It shortens the time on mechanical ventilation.

## When is prone position recommended in ARDS?

In moderate to severe ARDS with PaO2/FiO2 below 150 mmHg despite optimised ventilation, in long sessions (WHO 12–16 h; ESICM 16 h or more).

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## Elsewhere in DurgiPedia

- [Oxygenation: SpO₂, PaO₂, cyanosis and oxygen therapy](https://durgical.com/en/physiology/oxygenation-spo-pao-cyanosis-and-oxygen-therapy/)

## Connections

## Related 3

- [Caring for the ventilated patient: modes and settings in general terms, the hourly check and what to record](https://durgical.com/en/nursing/caring-for-the-ventilated-patient-modes-and-settings-in-general-terms-the-hourly/)
- [Prone positioning: the team, the turn, protecting tubes, eyes and pressure points](https://durgical.com/en/nursing/prone-positioning-the-team-the-turn-protecting-tubes-eyes-and-pressure-points/)
- [The patient on neuromuscular blockers: sedation first, train-of-four, eye care and skin](https://durgical.com/en/nursing/the-patient-on-neuromuscular-blockers-sedation-first-train-of-four-eye-care-and/)

## Related conditions 1

- [Acute respiratory distress syndrome (ARDS)](https://durgical.com/en/conditions/acute-respiratory-distress-syndrome/)

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Educational content for students; it does not replace your institution's protocols, supervised clinical training or a prescriber's order. Dose-calculation examples use made-up numbers: they are educational, not a clinical order.

Sources: [Clinical management of COVID-19: living guideline, 18 August 2023](https://www.who.int/publications/i/item/WHO-2019-nCoV-clinical-2023.2) (World Health Organization, 2023); [Clinical care for severe acute respiratory infection: toolkit, update 2022 (COVID-19 adaptation), tools 9.9 and 9.14](https://www.who.int/publications/i/item/clinical-care-of-severe-acute-respiratory-infections-tool-kit) (World Health Organization, 2022); [ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies](https://pmc.ncbi.nlm.nih.gov/articles/PMC10354163/) (Intensive Care Medicine (open access, PMC), 2023); [Prone position in ARDS patients: why, when, how and for whom](https://pmc.ncbi.nlm.nih.gov/articles/PMC7652705/) (Intensive Care Medicine (open access, PMC), 2020).

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Representative model, for educational purposes only.

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Source: https://durgical.com/en/nursing/nursing-the-patient-with-ards-lung-protective-ventilation-oxygenation-goals-flui/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/nursing/nursing-the-patient-with-ards-lung-protective-ventilation-oxygenation-goals-flui/
