[Durgical](https://durgical.com/en/) › [DurgiPedia](https://durgical.com/en/durgipedia/) › [Nursing](https://durgical.com/en/nursing/) › [Medical–surgical nursing](https://durgical.com/en/nursing/areas/med-surg/) › Urinary tract infection and pyelonephritis: the clean specimen, fluids, teaching and catheter-related infection

# Urinary tract infection and pyelonephritis: the clean specimen, fluids, teaching and catheter-related infection

- Safe practice

In a urinary infection the nurse takes a clean sample, encourages fluids, gives the antibiotics ordered, watches for sepsis and protects catheters.

Updated Nov 13, 2026

## Key points

- Clean-catch midstream sample: clean, pass the first urine into the toilet, collect the middle part, do not touch the inside of the cup.
- With a catheter: disinfect the sampling port and aspirate with a sterile syringe; never take urine from the bag.
- Fever, chills, flank pain or vomiting suggest kidney infection: report it.
- In older adults, new confusion may be the only sign of a UTI.
- Catheters: only when indicated, closed system, bag below the bladder and off the floor, removed as soon as possible.
- Do not routinely screen catheterised patients without symptoms for bacteria in the urine.

## What it is

A urinary tract infection may stay in the bladder or reach the kidneys (pyelonephritis). Bladder infection causes burning, frequency, urgency, cloudy or bloody urine and lower abdominal pressure; kidney infection adds fever, chills, flank pain, nausea and vomiting, and in older people confusion may be the only sign. The nurse's work is a correct specimen (clean-catch or from the catheter sampling port, never from the bag), fluids unless restricted, the antibiotics on time and to the end, watching for sepsis, and preventing catheter-associated infection: a catheter only when indicated, a closed system, free flow and removal as soon as possible.

## What it requires

- Recognise bladder versus kidney symptoms.
- A specimen collected without contamination, labelled and sent as the protocol sets.
- Antibiotics given on time and completed even when the patient feels better.
- Every urinary catheter has a current indication.

## How it is applied (and why)

- Ask about burning, frequency, urgency and the look and smell of the urine — they point to a bladder infection.
- Check temperature and ask about chills, flank pain and nausea — they suggest the kidneys are infected.
- In an older adult with new confusion, think of a UTI and report it — it may be the only sign.
- Teach the clean-catch midstream method and check the sample — contamination from the skin gives false results.
- With a catheter, disinfect the sampling port and aspirate with a sterile syringe — urine in the bag is contaminated.
- Label the sample and send it as the protocol sets — if it cannot go at once, store it as the laboratory instructs.
- Encourage fluids, mostly water, unless the patient has a fluid limit — they are part of the advice for bladder and kidney infections.
- Give the antibiotics as ordered and teach to finish them — stopping early lets the infection come back.
- Check pulse, blood pressure, breathing and mental status — sepsis is the dangerous complication.
- Ask every day whether the catheter is still needed and keep the system closed and draining — duration drives catheter infection.

## In nursing practice

- Most bladder infections improve within 24 to 48 hours of starting treatment; kidney infection may take a week or more.
- Sepsis risk is higher in very old adults and in people with weak immunity.
- Recurrence soon after treatment needs reporting.
- Catheter care: hand hygiene before and after handling, routine meatal hygiene with the daily wash, no antiseptic on the meatus.

## Common mistakes

- Taking the urine sample from the drainage bag.
- Changing catheters or bags on a fixed schedule instead of when clinically needed.
- Leaving the bag on the floor or above the bladder, or the tubing kinked.
- Sending urine cultures from catheterised patients without symptoms.
- Not reporting fever, flank pain, low blood pressure or new confusion.

## Test yourself

Think of the answer, then tap the question to see it.

## Where does the nurse take a urine culture from a patient with an indwelling catheter?

From the disinfected needleless sampling port with a sterile syringe; never from the drainage bag, which is contaminated.

## Which signs suggest the infection has reached the kidneys?

Fever, chills, flank or back pain, nausea and vomiting, and in older people confusion.

## Should catheterised patients without symptoms be screened routinely for bacteria in the urine?

No; CDC advises against routine screening for asymptomatic bacteriuria in catheterised patients.

## Where should the catheter drainage bag be kept?

Below the level of the bladder at all times and off the floor, with the tubing free of kinks.

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## Elsewhere in DurgiPedia

- [Urinary symptoms: dysuria, frequency, oliguria and hematuria](https://durgical.com/en/clinical-exam/urinary-symptoms-dysuria-frequency-oliguria-and-hematuria/)

## Connections

## Related 4

- [Specimen collection: urine, stool, sputum and swabs](https://durgical.com/en/nursing/specimen-collection-urine-stool-sputum-and-swabs/)
- [Indwelling catheter care and removal](https://durgical.com/en/nursing/indwelling-catheter-care-and-removal/)
- [Preventing healthcare-associated infections: the care bundles](https://durgical.com/en/nursing/preventing-healthcare-associated-infections-the-care-bundles/)
- [Urinary catheterization](https://durgical.com/en/nursing/urinary-catheterization/)

## Related conditions 3

- [Urinary tract infection (acute cystitis)](https://durgical.com/en/conditions/urinary-tract-infection/)
- [Acute pyelonephritis](https://durgical.com/en/conditions/acute-pyelonephritis/)
- [Catheter-associated urinary tract infection](https://durgical.com/en/conditions/catheter-associated-urinary-tract-infection/)

[← All of nursing](https://durgical.com/en/nursing/)

Educational content for students; it does not replace your institution's protocols, supervised clinical training or a prescriber's order. Dose-calculation examples use made-up numbers: they are educational, not a clinical order.

Sources: [Urinary tract infection - adults, MedlinePlus Medical Encyclopedia](https://medlineplus.gov/ency/article/000521.htm) (MedlinePlus, US National Library of Medicine, 2026); [Clean catch urine sample, MedlinePlus Medical Encyclopedia](https://medlineplus.gov/ency/article/007487.htm) (MedlinePlus, US National Library of Medicine, 2024); [Guideline for Prevention of Catheter-Associated Urinary Tract Infections (2009): Summary of Recommendations](https://www.cdc.gov/infection-control/hcp/cauti/summary-of-recommendations.html) (Centers for Disease Control and Prevention (CDC), HICPAC, 2009); [Nursing Skills (Open RN), 11.5 Obtaining Urine Specimen for Culture](https://med.libretexts.org/Courses/University_of_South_Carolina_Upstate/Nursing_Skills_(OpenRN)/11%3A_Facilitation_of_Elimination/11.05%3A_Obtaining_Urine_Specimen_for_Culture) (Open RN, Wisconsin Technical College System (CC BY 4.0), LibreTexts, 2021).

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Representative model, for educational purposes only.

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Source: https://durgical.com/en/nursing/urinary-tract-infection-and-pyelonephritis-the-clean-specimen-fluids-teaching-an/
License: CC BY 4.0 (https://creativecommons.org/licenses/by/4.0/). Cite as: DurgiPedia (durgical.com), https://durgical.com/en/nursing/urinary-tract-infection-and-pyelonephritis-the-clean-specimen-fluids-teaching-an/
