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Placebos and deception in clinical practice

  • Topic

Giving a placebo while letting the patient believe it is an active treatment is deception. There are honest options, such as open-label placebo.

Updated

What it is

The placebo effect is real: expectations and the relationship with the doctor change symptoms such as pain or nausea. The ethical problem is deception: giving something inert while letting the patient believe it is an active treatment violates truthfulness and consent, and if discovered it destroys trust. Impure placebos are also common: an active treatment used without an indication (for example, an antibiotic for a viral infection), which also exposes the patient to harm. An honest alternative is open-label placebo: the patient is told it is a placebo; in a 2010 trial in irritable bowel syndrome it improved symptoms compared with no treatment. The therapeutic privilege page covers another form of non-disclosure; placebo in research is covered under equipoise and placebo controls.

Key facts

  • Forms of deception: lying, withholding something important, or partial disclosure that misleads; all three can damage trust.
  • In favour of deceptive placebo it is said that it relieves without adverse effects; against it, that it violates autonomy, risks trust and feeds paternalism.
  • Nocebo effect: mentioning adverse effects can make them more likely; this does not justify withholding them, but it does call for care in how they are said.
  • Prescribing without an indication «to give something» exposes the patient to adverse effects and, with antibiotics, to bacterial resistance.
  • Placebo in research is different: the participant knows they may receive it and consents.

In clinical practice

  • A patient with chronic pain asks for «something more»: explain, offer evidence-based measures and close follow-up, rather than a drug without an indication.
  • If an open-label placebo is offered, say: «this is a pill with no active ingredient; some people improve with it», and the patient decides.
  • A relative asks «give him water and tell him it's a painkiller»: this is not done; the cause of the symptom is sought and treated.
  • To reduce nocebo, present adverse effects with frequencies and explain what will be done if they occur.
  • Ley 23 de 1981, art. 12: the doctor uses only diagnostic or therapeutic means accepted by legally recognized scientific institutions.
  • Ley 23 de 1981, art. 10, parágrafo: the doctor does not subject the patient to medical or surgical treatments that are not justified.
  • Ley 1751 de 2015, art. 10 d): right to clear, appropriate and sufficient information about procedures and their risks.
  • Official texts checked on 2026-11-13 at minsalud.gov.co and normograma.supersalud.gov.co.

Test yourself

Think of the answer, then tap the question to see it.

Why is deceptive placebo ethically problematic?

Because the patient does not consent to what they receive: it violates truthfulness and autonomy, and if discovered it destroys trust in the doctor.

What is an impure placebo?

An active treatment used without an indication for that problem, such as an antibiotic for a viral infection; it also exposes the patient to adverse effects.

What did the 2010 open-label placebo trial in irritable bowel syndrome show?

That people who took pills knowing they were placebos improved more than those who received no treatment.

Which article of Ley 23 de 1981 limits the doctor to accepted therapeutic means?

Article 12: the doctor uses only diagnostic or therapeutic means accepted by legally recognized scientific institutions.

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Educational content on ethics and health law; not legal advice. Laws and case law change: each page links the official text and says when it was last checked. For a real case, read the text in force and ask a lawyer or the medical ethics tribunal.

Sources: Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome (PLOS ONE, 2010); Informed Consent (Stanford Encyclopedia of Philosophy, 2025); Ley 23 de 1981, por la cual se dictan normas en materia de ética médica (Ministerio de Salud y Protección Social, 1981); Ley Estatutaria 1751 de 2015, que regula el derecho fundamental a la salud (Superintendencia Nacional de Salud, Normograma, 2015).

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