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Strabismus in children: esotropia, exotropia, pseudostrabismus

  • Topic

A squint in a child is never outgrown and can hide a tumour or cataract. Some just look crossed (pseudostrabismus); a true squint is referred.

Updated

See it in 3D: Medial rectus · Lateral rectus · Abducens nerve (VI)

What it is

Strabismus is a misalignment of the eyes. In children it matters for three reasons: it causes amblyopia, it can be the first sign of a serious eye disease (retinoblastoma, cataract), and it can signal neurological disease. Many infants look cross-eyed because of a wide nasal bridge (pseudostrabismus), but true strabismus does not resolve with age and needs an eye exam.

Key facts

  • Pseudostrabismus: wide nasal bridge and epicanthal folds, symmetrical corneal light reflexes, normal cover test.
  • Infantile esotropia: a large inward turn starting before about 6 months.
  • Accommodative esotropia: starts around 2 to 3 years, with long-sightedness; glasses straighten the eyes.
  • Intermittent exotropia: an eye drifts out when tired or daydreaming; the child closes one eye in bright light.
  • Sixth nerve palsy in a child: after a viral illness, or from raised intracranial pressure or a tumour.

In clinical practice

  • Intermittent misalignment in the first months of life is normal; a constant deviation at any age, or any deviation after about 4 months, is not.
  • Every child with strabismus needs a red reflex test and a dilated fundus exam to exclude retinoblastoma and cataract.
  • Treatment combines glasses, amblyopia treatment and, when needed, surgery on the eye muscles.

Next step / Initial management

  • Any constant strabismus, or strabismus after about 4 months: paediatric ophthalmology, with cycloplegic refraction and fundus exam.
  • Strabismus with an abnormal red reflex or leukocoria: urgent referral (retinoblastoma).
  • New strabismus with headache, vomiting or other neurological signs: urgent brain imaging.
  • Pseudostrabismus with a normal light reflex and cover test: reassure and recheck at the next well-child visit.

Test yourself

Think of the answer, then tap the question to see it.

How is pseudostrabismus recognised?

By symmetrical corneal light reflexes and a normal cover test in a child with a wide nasal bridge or epicanthal folds.

What characterises accommodative esotropia?

An inward turn starting around 2 to 3 years in a long-sighted child, corrected by glasses for the hyperopia.

Why does every child with strabismus need a fundus exam?

Because strabismus can be the first sign of retinoblastoma or a cataract.

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Connections

← All of ophthalmology

Educational content; not a clinical guideline and no substitute for assessment by a health professional. For sudden visual loss, severe eye pain, a chemical burn or an eye injury, go to an emergency department at once.

Sources: Strabismus (StatPearls Publishing (NCBI Bookshelf), 2026); Esotropia (StatPearls Publishing (NCBI Bookshelf), 2023); Intermittent Exotropia (StatPearls Publishing (NCBI Bookshelf), 2025).

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