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Interpectoral nodes !

The interpectoral nodes are a small group of lymph nodes between the two chest muscles (pectoralis major and minor); breast cancer can spread to them.

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What it is

A few nodes between pectoralis major and pectoralis minor (level II).

What it does

Drain part of the upper breast straight to the central and apical nodes, skipping the anterior group.

Key facts

Where
Between pectoralis major and pectoralis minor (Rotter's nodes)
Drains
Upper breast and pectoral region
Into
Apical axillary nodes

Relations

In front
Deep surface of the pectoralis major
Behind
Pectoralis minor and its fascia (clavipectoral fascia)
Contents
A few nodes in fat with the pectoral branches of the thoracoacromial artery and the lateral pectoral nerve
Above
Apical axillary lymph nodes and the infraclavicular region

How to find it

Not palpable. In surgery they are found by lifting the pectoralis major off the pectoralis minor; on imaging they are sought in the fat plane between the two muscles.

On imaging

CT, MRI or PET-CT can show an enlarged node in the plane between the pectoral muscles; ultrasound reaches it in some patients.

Common problems

  • Can hold breast cancer even when the lower axillary nodes are clear.

How it is diagnosed

Examination of the armpit and ultrasound with a needle biopsy; in breast cancer, the sentinel node is found with a tracer during surgery.

Treatment

  • Sentinel node biopsy: only the first one to three nodes are removed and checked.
  • Axillary dissection (levels I–II) or radiotherapy when the nodes contain cancer; arm swelling (lymphoedema) is the main risk.

Clinical notes

  • Grouped with level II nodes in many surgical systems (level I lateral, level II behind and level III medial to pectoralis minor); some texts list them separately
  • Removing them puts the medial and lateral pectoral nerves at risk; injury weakens and wastes the pectoralis major
  • Breast cancer in men follows the same lymph pathways, including these nodes
  • After mastectomy, involved nodes left between the pectoral muscles are a recognised site of regional recurrence, which may appear as a lump under the pectoralis major

Anatomical variants

  • Not found in every person, and their number varies when present; some surgical series find none on careful dissection

Test yourself

Think of the answer, then tap the question to see it.

Where do the interpectoral (Rotter) nodes lie?

Between the pectoralis major and minor, along the pectoral branches of the thoracoacromial artery and the lateral pectoral nerve.

Why do interpectoral nodes matter in breast cancer?

They can receive breast lymph directly and carry metastases that bypass the lower axillary levels.

Which nerves are at risk when interpectoral nodes are removed, and with what result?

The medial and lateral pectoral nerves; injury weakens and wastes the pectoralis major.

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Educational information, not medical advice. For any symptom, see a health professional.

Its names

Official Latin (TA2)
nodi interpectorales TA2 5242
Official Spanish (DeCS)
Nódulos linfáticos interpectorales
English (TA2)
Interpectoral nodes
Also called
Rotter's nodes

Sources: Terminologia Anatomica (TA2); Anatomy, Thorax: Mammary Gland; Anatomy, Shoulder and Upper Limb, Axillary Lymph Nodes.

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Representative model, for educational purposes only.