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Central retinal artery !

The central retinal artery runs inside the optic nerve and spreads over the retina to feed it; a blockage causes sudden, painless loss of vision.

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What it is

Vessels running inside the optic nerve and spreading over the retina.

What it does

Feed the inner retina; a blocked artery causes sudden painless vision loss.

Key facts

Origin
Ophthalmic artery; enters the optic nerve ~1 cm behind the eye
Branches
Four branches over the retina (superior/inferior, nasal/temporal); end arteries
Supplies
Inner retina (occlusion = sudden painless loss of vision; cherry-red spot)

Relations

Course
Arises from the ophthalmic artery near the optic canal, runs forward below the optic nerve, pierces its dural sheath about 1 cm behind the eyeball and travels in the centre of the nerve to emerge at the optic disc, where it divides
Deep
Over the retina its branches run in the nerve fibre layer under the internal limiting membrane, facing the vitreous body; where they cross veins they share a sheath (arteriovenous crossings)

How to find it

On fundoscopy its branches are the narrower, brighter red vessels leaving the disc, with a central light reflex; they are thinner than the veins beside them. Following the arcades out from the disc shows the four main branches.

Examination

  • Fundoscopy: whitened, swollen retina, cherry-red spot, thin arteries, sometimes an embolus visible at a branch point
  • Swinging flashlight test: a relative afferent pupillary defect in the affected eye
  • Inflammatory markers and temporal artery assessment in older patients, looking for giant cell arteritis

On imaging

Fluorescein angiography shows delayed arterial filling; OCT shows a thick, bright inner retina early and thinning later; the stroke workup includes carotid imaging, an ECG and imaging of the heart.

Clinical notes

  • Branch retinal artery occlusion causes a sector of field loss matching the territory supplied
  • Hypertensive and arteriosclerotic changes are seen directly in its branches: narrowing, copper or silver wiring, and nicking where arteries cross veins
  • Central retinal vein occlusion, of its companion vein, looks very different: swollen tortuous veins and haemorrhages across the whole retina

Anatomical variants

  • Cilioretinal artery: a branch of the posterior ciliary circulation emerging at the temporal edge of the disc in a sizeable minority of eyes (figures vary between texts); it can spare central vision in an occlusion

Development

It is the persistent proximal part of the hyaloid artery, whose segment crossing the vitreous to the lens regresses before birth.

Test yourself

Think of the answer, then tap the question to see it.

What are the signs of central retinal artery occlusion?

Sudden painless loss of vision in one eye, a pale retina with a cherry-red spot, a relative afferent pupillary defect and segmented (boxcar) blood columns.

Which cause must be ruled out in an older patient with central retinal artery occlusion?

Giant cell arteritis; other main causes are emboli from the carotid artery (Hollenhorst plaques) or the heart.

What is amaurosis fugax and how is it investigated?

A brief curtain over one eye: a transient ischaemic attack of the retina, with the same workup as a stroke.

How can a cilioretinal artery change the effect of a central retinal artery occlusion?

This branch of the posterior ciliary circulation, present in a sizeable minority of eyes, can spare central vision.

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Educational information, not medical advice. For any symptom, see a health professional.

Its names

Official Latin (TA2)
arteria centralis retinae TA2 4470
Official Spanish (DeCS)
Arteria Retiniana DeCS D012161
English (TA2)
Central retinal artery
Also called
Zinn's artery

Sources: Terminologia Anatomica (TA2); DeCS; Central Retinal Artery Occlusion; Anatomy, Head and Neck, Eye Arteries; Tratado de anatomía humana (9.ª ed.), tomo II, Libro IV, sección 2 Arterias, caps. I-III (sistema de la arteria pulmonar; aorta y ramas del cayado hasta la carótida interna).

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Representative model, for educational purposes only.

Central retinal artery highlighted on the Durgical 3D model