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Vitreous !

The vitreous is the clear gel filling the back of the eye; it keeps the eye's shape, and clumps in it cast the shadows called floaters.

Official name: Vitreous body

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What it is

The clear gel filling the back of the eye.

What it does

Keeps the eye's shape; clumps in it cast the shadows called floaters.

Key facts

Where
Fills the space between the lens and the retina (~80% of the eye)
Blood supply
Avascular
Function
Keeps the eye's shape; transparent path for light

Relations

In front
Back of the lens, which sits in its hyaloid fossa, and the zonular fibres
Behind
Optic disc and macula, where the posterior hyaloid face adheres
Superficial
Retina, against the internal limiting membrane, and the pars plana of the ciliary body at its base
Contents
Cloquet canal, the path of the former hyaloid artery from disc to lens, and scattered cells (hyalocytes)

How to find it

Seen at the slit lamp just behind the lens (anterior vitreous) and with the ophthalmoscope as a clear space; floaters and pigment drift in it as the eye moves.

Examination

  • Slit lamp of the anterior vitreous: pigment cells (tobacco dust, Shafer sign) after a posterior vitreous detachment strongly suggest a retinal tear
  • Fundoscopy: a floating ring in front of the disc (Weiss ring) marks a posterior vitreous detachment

On imaging

B-scan ultrasound shows the detached posterior hyaloid, and any retinal detachment, when blood blocks the view; OCT shows vitreomacular traction.

Common problems

  • Floaters: specks and cobwebs from clumping gel, common with age.
  • Posterior vitreous detachment: the gel peels off the retina; a sudden burst of floaters needs a retina check.
  • Vitreous haemorrhage, often from diabetic vessels.

How it is diagnosed

Dilated eye exam; ultrasound when blood blocks the view.

Treatment

  • Usually no treatment for floaters.
  • Vitrectomy (removing the gel) for persistent bleeding or retinal problems.

Clinical notes

  • Injections into the vitreous (anti-VEGF drugs, steroids, antibiotics) and vitrectomy instruments enter through the pars plana
  • Endophthalmitis: infection of the vitreous after surgery or injury; a sample is taken from it for culture
  • Asteroid hyalosis: many small white calcium-lipid particles, usually harmless
  • Persistent fetal vasculature (persistent hyperplastic primary vitreous) causes leukocoria and a small eye in infants

Anatomical variants

  • Remnants of the fetal hyaloid artery are common and harmless: a small dot on the back of the lens capsule (Mittendorf dot) or a tuft of glial tissue on the disc (Bergmeister papilla)

Development

The primary vitreous, which holds the hyaloid vessels, is replaced by the avascular secondary vitreous; the tertiary vitreous forms the zonular fibres.

Test yourself

Think of the answer, then tap the question to see it.

Why are new flashes and floaters checked with a dilated retinal exam?

They may mean a posterior vitreous detachment that has torn the retina, which can lead to retinal detachment.

Where is the vitreous body attached most firmly?

At the vitreous base over the ora serrata; less so at the optic disc, the macula and along vessels.

What does «tobacco dust» (Shafer sign) in the anterior vitreous suggest?

A retinal tear, after a posterior vitreous detachment.

What is Terson syndrome?

Bleeding into the eye (vitreous haemorrhage) with a subarachnoid haemorrhage.

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Educational information, not medical advice. For any symptom, see a health professional.

Its names

Official Latin (TA2)
corpus vitreum TA2 6809
Official Spanish (DeCS)
Cuerpo Vítreo DeCS D014822
English (TA2)
Vitreous body
Also called
vitreous humour

Sources: Terminologia Anatomica (TA2); DeCS; Posterior Vitreous Detachment; Anatomy, Head and Neck, Eye.

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Representative model, for educational purposes only.

Vitreous highlighted on the Durgical 3D model