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Hypertensive emergency: target-organ signs !

  • Syndrome

Very high blood pressure is an emergency when it is already harming the brain, eyes, heart, aorta or kidney; the exam looks for that harm.

Updated 2026-11-01

See it in 3D: Retina · Kidneys · Left ventricle · Thoracic aorta

What it is

A hypertensive emergency is a severe rise in blood pressure, usually 180/120 mmHg or more, with acute target-organ damage. Without acute damage it is severe uncontrolled hypertension (formerly 'urgency'). What defines the emergency is the damage, not the number alone.

Key findings

  • Brain: severe headache, vomiting, confusion, seizures, visual disturbance (hypertensive encephalopathy); focal deficit (stroke).
  • Eyes: blurred vision; fundus with hemorrhages, cotton-wool spots or papilledema.
  • Heart: chest pain (acute coronary syndrome), dyspnea with crackles (acute pulmonary edema).
  • Aorta: tearing back pain, pressure difference between arms. Kidney: oliguria, hematuria, proteinuria, rising creatinine.
  • Pregnancy: pressure of 160/110 mmHg or more with headache, visual change, epigastric pain or seizures: severe preeclampsia or eclampsia.

Pathophysiology

  • Very high pressure overwhelms autoregulation of cerebral and renal flow: cerebral edema, fibrinoid necrosis of arterioles, hemorrhages.
  • The left ventricle faces a very high afterload: ischemia and acute pulmonary edema.
  • The aortic wall is under more stress: risk of dissection.
  • Arteriolar changes show in the retina: flame hemorrhages, cotton-wool spots and papilledema.

Common causes

  • Stopping antihypertensive treatment, the most common cause.
  • Renovascular hypertension, acute glomerulonephritis, chronic kidney disease.
  • Cocaine, amphetamines, abrupt withdrawal of clonidine or beta-blockers; pheochromocytoma.
  • Preeclampsia and eclampsia.

Tests that confirm it

  • Confirm the reading with the right cuff, in both arms, with the patient at rest.
  • Creatinine, urinalysis, electrolytes, blood count with smear (microangiopathic hemolysis), troponin, ECG.
  • Fundoscopy; head CT if there are neurological signs; CT angiography if dissection is suspected.

Test yourself

Think of the answer, then tap the question to see it.

What separates a hypertensive emergency from severe hypertension without an emergency?

Acute target-organ damage (brain, eye, heart, aorta, kidney); the number alone does not define it.

Which fundus findings indicate severe hypertensive retinopathy?

Flame hemorrhages, cotton-wool spots and papilledema.

Which symptoms suggest hypertensive encephalopathy?

Severe headache, vomiting, confusion, visual disturbance and seizures.

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See it in 3D

The structures of Durgical's 3D anatomy where it is found.

← All of the clinical exam

Educational content on the clinical exam; it is learned and practised under supervision. It does not replace assessment by a health professional and is not for self-diagnosis.

Sources: Malignant hypertension: MedlinePlus Medical Encyclopedia (MedlinePlus, U.S. National Library of Medicine, 2026); Chest pain: MedlinePlus Medical Encyclopedia (MedlinePlus, U.S. National Library of Medicine, 2026); 24.3 Nursing Assessment - Clinical Nursing Skills | OpenStax (OpenStax (Rice University), 2024).

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Representative model, for educational purposes only.