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Seminal vesicles !

The seminal vesicles are two coiled glands behind the bladder; they make most of the fluid of semen, rich in fructose that feeds the sperm.

Official name: Seminal gland

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What it is

Two coiled, sac-like glands, about 5 cm long, behind the bladder and above the prostate.

What it does

Make most of the fluid of semen (rich in fructose, an energy source for sperm); each joins a ductus deferens to form an ejaculatory duct.

Key facts

Where
Paired coiled sacs behind the bladder base and above the prostate, lateral to the ampullae of the ductus deferens; in front of the rectum
Blood supply
Inferior vesical and middle rectal arteries; artery to the ductus deferens
Nerve
Pelvic plexus: sympathetic fibres (T10–L2) contract its smooth muscle at emission
Function
Alkaline, fructose-rich fluid that makes up most of the semen volume (about 60–70%); its duct joins the ductus deferens to form the ejaculatory duct; invasion by prostate cancer raises the stage

Relations

In front
Back (base) of the urinary bladder
Behind
Rectum, separated by the rectoprostatic (Denonvilliers) fascia
Medial
Ampullae of the ductus deferens, which lie between the two vesicles
Below
Base of the prostate, where each duct joins a ductus deferens to form an ejaculatory duct
Above
Ureters, which reach the bladder near their upper tips, and the rectovesical pouch

How to find it

Usually out of reach on digital rectal examination; when enlarged, firm or invaded by tumour they may be felt above the prostate.

On imaging

Transrectal ultrasound shows them as paired, symmetric structures above the prostate, like a bow tie. On T2-weighted MRI they are bright and convoluted; loss of that bright signal, a mass or asymmetry suggests invasion by prostate cancer. Dilated vesicles can point to ejaculatory duct obstruction.

Common problems

  • Rarely diseased on their own; they can be inflamed together with the prostate.
  • Prostate cancer can spread into them, which changes its stage.

How it is diagnosed

MRI of the prostate; transrectal ultrasound.

Treatment

  • Removed together with the prostate in a radical prostatectomy.

Clinical notes

  • Blood in the semen (haematospermia) usually comes from the seminal vesicles or prostate and in young men is mostly benign
  • Their tips lie close to the pelvic plexus, so their dissection in prostatectomy can harm the nerves of erection

Anatomical variants

  • Agenesis is rare and often comes with other mesonephric anomalies on the same side, such as renal agenesis; a seminal vesicle cyst with an absent kidney on that side is Zinner syndrome

Development

Bud from the lower end of the mesonephric (Wolffian) duct, which also gives the ureteric bud; this explains their link with kidney and ureter anomalies on the same side.

Test yourself

Think of the answer, then tap the question to see it.

Do the seminal vesicles store sperm?

No; they secrete alkaline, fructose-rich fluid making up most of the semen volume, including proteins that make semen clot.

What stage does seminal vesicle invasion by prostate cancer represent?

T3b; it worsens the outlook, and the vesicles are removed with the prostate in radical prostatectomy.

What is Zinner syndrome?

A seminal vesicle cyst with an absent kidney on the same side, reflecting their shared mesonephric (Wolffian) duct origin.

Where does haematospermia usually come from, and what is its usual nature in young men?

From the seminal vesicles or prostate; in young men it is mostly benign.

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Educational information, not medical advice. For any symptom, see a health professional.

Its names

Official Latin (TA2)
glandula vesiculosa
Official Spanish (DeCS)
Glándula seminal
English (TA2)
Seminal gland
Also called
seminal vesicle · seminal glands

Sources: Anatomy, Abdomen and Pelvis, Seminal Vesicle.

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Representative model, for educational purposes only.

Seminal vesicles highlighted on the Durgical 3D model